Statin Use Prolongs Patient Survival after Renal Transplantation
نویسندگان
چکیده
منابع مشابه
Impact of Statin Use After Heart Transplantation
Structured summary 2 Provide a structured summary including, as applicable: background; objectives; data sources; studyeligibility criteria, participants, and interventions; study appraisal and synthesis methods; results;limitations; conclusions and implications of key findings; systematic review registration number.2
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Background and Objective: Some neurologic complications may be detected after renal transplantation in children including tremor, peripheral neuropathy, altered level of consciousness and seizure. The aim of our study was to detect the prevalence of seizure after renal transplantation and its risk factors in pediatric age groups. Methods: In this descriptive study, 102 patients 5-14 yea...
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In a series of 404 consecutive first cadaver kidney transplants performed since 1967 the actuarial five- and 10-year survival of patients were 61% and 47% respectively and of grafts 46% and 36%. In more than four-fifths of the patients surviving these intervals the original cadaveric grafts were functioning at these times, and most of the remainder were sustained by subsequent grafts. Although ...
متن کاملStatin use after renal transplantation: a systematic quality review of trial-based evidence.
BACKGROUND AND OBJECTIVES HMG-CoA reductase inhibitor (statin) therapy reduces cardiovascular risk in the general population and may modulate rejection in solid organ transplant recipients. We assessed whether current clinical evidence supports the use of statins to improve cardiac and/or renal outcomes after kidney transplantation. METHODS We performed a systematic review of randomized, cont...
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Interaction between C5a, a product of complement activation, and its receptor (C5aR) upregulates antigen-specific T cell responses by modulating the activation of antigen-presenting cells and T cells. Whether this C5a-C5aR interaction contributes to the immune responses that promote renal allograft rejection is unknown. Here, we found that deficiency of C5aR in both graft and recipient reduced ...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2008
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2008090925